Prempak-c - Information, specialists, frequent questions.

Usage of Prempak-c

Indications: HRT in non-hysterectomised women for menopausal symptoms. Prevention of postmenopausal osteoporosis
Contra Indications: Cancer of breast, genital tract or other oestrogen-dependent carcinoma, undiagnosed vaginal bleeding or endometriosis. Active thrombophlebitis or thromboembolic disorders. Severe cardiac, hepatic or renal disease. Dubin-Johnson or Rotor syndromes. Pregnancy, lactation

Adverse and side effects

GI upset, nausea, vomiting, weight gain, breast tenderness and enlargement, breakthrough bleeding, headache, dizziness, impaired liver function, cholestatic jaundice, epistaxis, migraine, thromboembolic disorders, exacerbation of varicose veins, increased blood pressure, transient erythema, generalised pruritus. REASONS FOR IMMEDIATE DISCONTINUATION OF TREATMENT: Occurence of migraine-type headaches for the first time, frequent severe headaches, acute visual disturbances, signs of thrombophlebitis or thromboembolism, or any other possible prodromal symptoms of vascular occlusion. Rise in blood pressure. Jaundice. Pregnancy. Discontinue six weeks before major elective surgery and during immobilisation entailing risk of thrombosis

Special precautions

History or increased risk of thromboembolic disorders. Mild chronic liver disease; monitor liver function every 8 to 12 weeks. Closely monitor patients with cholelithiasis, otosclerosis, migraine, multiple sclerosis, epilepsy, diabetes, hypertension, porphyria, uterine fibroids, tetany. Examine blood pressure, pelvic organs and breasts (particularly those with fibrocystic disease of the breast or a family history of breast cancer) before and regularly during treatment. If breakthrough bleeding is persistent, perform endometrial assessment, which may include biopsy

Questions about Prempak-c

Our experts have answered 3 questions about Prempak-c

 Radwan Faraj
Radwan Faraj
Gynaecologist
Sheffield
I would not rush and said it has not worked as yet
Probably it will be reasonable to finish at least the first pack (month) before disregarding this effective HRT

Remember…
1 answers

Mr. Tarek Gelbaya
Mr. Tarek Gelbaya
Gynaecologist
Leicester
With prempak- C, it is normal to have regular bleeding like a period every month. It can take between 3-4 months before the bleeding become regular. Irregular bleeding after finishing the fourth…
1 answers

Mr. Philip David Kaloo
Mr. Philip David Kaloo
Gynaecologist
Cheltenham
If you mean to prevent / stop hot flushes and/or night sweats, most women will find some improvement within 72 hours.
1 answers

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