Harmogen - Information, specialists, frequent questions.

Usage of Harmogen

Indications: HRT for menopausal symptoms. Prevention of postmenopausal osteoporosis
Contra Indications: Known or suspected pregnancy; cardiovascular or cerebrovascular disorders, eg, thrombophlebitis, moderate to severe hypertension, hyperlipoproteinaemia, or a history of these conditions; known or supected oestrogen- dependent tumours; endometrial hyperplasia, uterine fibromyomata, undiagnosed vaginal bleeding; severe liver disease including Dubin-Johnson and Rotor syndromes; porphyria; active deep vein thrombosis, thromboembolic disorders, or a history of confirmed venous thromboembolism; known or suspected breast cancer

Adverse and side effects

GI upset, nausea, vomiting, weight gain, breast tenderness and enlargement, breakthrough bleeding, headache, dizziness, impaired liver function, cholestatic jaundice, epistaxis, migraine, thromboembolic disorders, exacerbation of varicose veins, increased blood generalised pruritus. REASONS FOR IMMEDIATE DISCONTINUATION OF TREATMENT: Occurence of migraine-type headaches for the first time, frequent severe headaches, acute visual disturbances, signs of thrombophlebitis or thromboembolism, or any other possible prodromal symptoms of vascular occlusion. Rise in blood pressure. Jaundice. Pregnancy. Discontinue four weeks before major elective surgery and during immobilisation entailing risk of thrombosis

Special precautions

History or increased risk of thromboembolic disorders. Mild chronic liver disease; monitor liver function every 8 to 12 weeks. Closely monitor patients with cholelithiasis, otosclerosis, migraine, multiple sclerosis, epilepsy, diabetes, hypertension, uterine fibroids, tetany. Examine blood pressure, pelvic organs and breasts (particularly those with fibrocystic disease of the breast or a family history of breast cancer) before and regularly during treatment. If breakthrough bleeding is persistent, perform endometrial assessment, which may include biopsy. Small or moderate increase in probability of having breast cancer - refer to Summary of Product Characteristics

What professionals prescribe Harmogen?

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