Trinordiol

Indications: Oral contraception
Contra Indications: 1. CARDIOVASCULAR History of arterial or venous thrombosis, family history of venous thrombosis, other known risk factors for venous thrombosis, clotting disorders, ischaemic heart disease, angina. Transient ischaemia. Valvular heart disease, atrial fibrillation, pulmonary hypertension. Sickle cell anaemia. 2. HEPATIC History of cholestatic jaundice of pregnancy. Disorders of hepatic excretion (Dubin-Johnson/Rotor syndromes). Infectious hepatitis of any type. Abnormal liver function tests. Porphyria, Liver adenoma. 3. OTHER Pemphigoid gestationis, haemolytic uraemic syndrome, chorea, otosclerosis. Hormone dependent carcinoma. Undiagnosed vaginal bleeding. Recent trophoblastic disease. Pregnancy

Drug description:
Generic name: Ethinylestradiol [ethinyloestradiol], levonorgestrel
Drug class description: Oestrogens / progestogens

Hypertension, Raynaud's disease, diabetes, varicose veins, asthma, severe depression, chronic renal disease, multiple sclerosis, renal dialysis, hyperprolactinaemia. Risk of arterial thrombosis associated increased with age, smoking and obesity. Examine blood pressure, pelvic organs and breasts before and regularly during treatment

Breast enlargement, bloating with fluid retention. Cramps and pains in the legs. Depression. Loss of libido. Headaches, nausea, vaginal discharge and cervical erosion. Weight gain. Breakthrough bleeding. Chloasma. REASONS FOR IMMEDIATE DISCONTINUATION OF TREATMENT: Occurrence of migraine-type headaches for the first time or frequent severe headaches. Acute visual or auditory disturbances. First signs of thrombophlebitis or thromboembolism. Rise in blood pressure. Jaundice. Pregnancy. Discontinue six weeks before major elective surgery and during immobilization. Post-operatively, they should normally be restarted two weeks after the patient is fully mobile. These recommendations need not apply to minor surgical procedures with short duration of anaesthesia and early mobilisation except minor procedures to the legs. When discontinuation is not possible, prophylactic low dose, sub- cutaneous heparin may be considered