Usage of Elleste Duet Conti
Indications: Treatment of menopausal symptoms such as night sweats and hot flushes in women at least one year past the menopause who have an intact uterus. Treatment of the postmenopausal sequelae of oestrogen withdrawal, including atrophic vaginitis
and atrophic urethritis
. Prophylaxis of postmenopausal osteoporosis in women at risk of developing fractures
Contra Indications: Known or suspected pregnancy. Known, suspected, or past history of breast cancer. Known or suspected oestrogen-dependent neoplasia. Vaginal bleeding of unknown aetiology. Active deep vein thrombosis, thromboembolic disorders, or a history of confirmed venous thromboembolism. Acute or chronic liver disease or history of liver disease where the liver function tests have failed to return to normal. Rotor's syndrome or Dubin-Johnson syndrome
. Severe cardiac or renal disease. Hypersensitivity to one or more of the ingredients. Pregnancy and lactation
Drug description Elleste Duet Conti
Drug description: Round, grey, biconvex, film- coated tablets embossed with 'P2' on one side
Generic name: Estradiol [oestradiol], norethisterone acetate
Drug class description: Oestrogens / progestogens
Special precautions Elleste Duet Conti
History or increased risk of thromboembolic disorders. Mild liver function every 8 to 12 weeks. Closely monitor patients with cholelithiasis, otosclerosis, migraine, multiple sclerosis, epilepsy, diabetes, hypertension, porphyria, uterine fibroids, tetany. Examine blood pressure, pelvic organs and breasts (particularly those with fibrocystic disease of the breast or a family history of breast cancer) before and regularly during treatment. If breakthrough bleeding is persistent, perform endometrial assessment, which may include biopsy
Adverse and side effects Elleste Duet Conti
GI upset, nausea, vomiting, weight gain, breast tenderness and enlargement, breakthrough bleeding, headache, dizziness, impaired liver function, cholestatic jaundice, epistaxis, migraine, thromboembolic disorders, exacerbation of varicose veins, increased blood pressure, transient erythema, generalised pruritus. REASONS FOR IMMEDIATE DISCONTINUATION OF TREATMENT: Occurence of migraine-type headaches for the first time, frequent severe headaches, acute visual disturbances, signs of thrombophlebitis or thromboembolism, or any other possible prodromal symptoms of vascular occlusion. Rise in blood pressure. Jaundice. Pregnancy. Discontinue six weeks before major elective surgery and during immobilisation entailing risk of thrombosis
Presentation Elleste Duet Conti
Elleste Duet Conti Tablets, estradiol 2mg, norethisterone acetate 1mg
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