Information about Botulinum toxin therapy
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I assume you mean Botox injection into the bladder? Yes retention of urine with the need to do self catheterisation, bladder infection and possibility of bladder scarring from multiple injections.
Botulinum toxin paralyses muscles and certain glands. This can be used for medical or cosmetic reasons: -Face muscles causing creases -Spastic muscle overactivity -Excessive sweating Using Botulinum toxin in these conditions can lead to improvement. Technically it is injected near the nerve-muscle junction or near the glands which are at the lower boarder of the skin.
Botox or botulinum toxin is the most potent nerve agent and produced by a bacterium called clostridium botulinum. This toxin can be produced commercially and diluted. Since this preparation does not contain the bacterium, no excess toxin can be produced. In commercially available concentrations this agent is relatively safe. For cosmetic reasons about 50 units are injected under or into the skin. The lethal dose is about 3000 units.
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