Question about MelanomaIs there genetic predisposition for having a lot of moles? Having a big amount of them means that there is higher chance of skin cancer?
Melanoma genetics is complex but there is a genetic component to having lots of moles. If you have more than 200 moles, if you have abnormal moles, if you or a close family member have had a melanoma, then all these count as genetic risk factors for development of melanoma. These risk factors do not apply to non-melanoma skin cancers.
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Studies have shown that your risk can be estimated by the presence of these risk factors and other acquired risk factors eg. several episodes of bad sun-burn as a child.
The more risk factors, the greater the chance of life-time melanoma.
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